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Milli-Q® Integral Water Purification System for Ultrapure Water

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Detailed introduction

Milli-Q® Integral is a unique combination of optimized water purification and monitoring technologies. It allows, in a single device, both pure (Type 2) and ultrapure (Type 1) water to be produced directly from potable water. This all-in-one concept offers several benefits:

·         Provides users with complete control over all water purification steps and the final water quality. 

·         Allows installation of a comprehensive water purification chain in a minimal amount of space. 

·         Eliminates the constraints of centralized water stations and their distribution loops (complexity, heavy maintenance, prolonged downtime, contamination).

Milli-Q® water • Best-in-class purity

To reach the most reliable ultrapure water quality, Milli-Q® Integral is built on an optimized purification sequence:

Elix® | First, Elix® pure water is produced from tap and delivered through the E-POD® (Elix®-Point-Of-Delivery) remote dispenser. To ensure a consistent source of high quality pure water, the patented Elix® module (EDI technology) is combined with Progard® complete pretreatment, intelligent reverse osmosis and bactericidal UV lamp technologies. Depending on daily volume needs, different production flow rates are available (3, 5, 10 & 15 L/h).

Storage | Pure water is then stored in a polyethylene storage tank, which has been designed to maintain consistent purity of stored water. The vent filter provides effective protection against airborne contaminants and the ASM, Automatic Sanitization Module, prevents biofilm formation. Water is then further processed by the Milli-Q® Integral to produce ultrapure water or it can be sent by a distribution pump to feed instruments such as a glassware washing machine.

Milli-Q® | To obtain Milli-Q water quality, purified water passes through a long-life dual wavelength UV lamp, which ensures organic molecule degradation by photooxidation. The Quantum® polishing cartridge then removes the remaining ionic and organic contaminants below trace levels. Finally, the ultrapure water recirculates through a loop to the Q-POD® (Quality-Point-Of-Delivery) dispenser, where an Application-Pak removes specific contaminants critical for experiments – Ultrapure water free of particulates, bacteria, pyrogens, nucleases, proteases, VOCs, endocrine disruptors and organics for LC.

Made only for Milli-Q® systems, Jetpore® virgin ion-exchange resin is used in all Milli-Q® purification cartridges. Selected for its exceptional performance, it can capture even the most weakly charged ions due to its kinetic capabilities. Both the Progard® and Quantum® cartridges incorporate RFID technology. This provides instant visibility on cartridge parameters and also ensures a safe & optimal performance of your system, giving you full traceability.

Q-POD® & E-POD® dispensers • Advanced technology

The Q-POD® and E-POD® dispensers simplify operation and display essential data in an easy-to-use and compact device.

·         Facilitate your daily lab work - The POD remote dispensers are always within reach. Their convenient and adaptable handling enables both intuitive and precise dispensing. The user can select either a specific volume with the autofill key or manually press the plunger. Their multicolor graphic display allows easy interaction with the system and provides information about water quantity and quality. 

·         Free up space on your bench - As only the POD is necessary for daily needs, the system can now be placed where it is most convenient – under the bench, on the wall… Up to three PODs can be used with each production unit at different locations within the same laboratory. 

·         Get the right water quality for your experiments – Fitted to each POD, an Application-Pak provides final polishing to match the water quality according to your application’s exact needs. A range of POD-Paks is available for you to select from.

 

Water Specifications

Milli-Q® Integral ultrapure water (Type 1)

Resistivity at 25 °C1

18.2 MΩ•cm

TOC2

≤ 5 ppb

Particulates (size > 0.22 μm)3

< 1 particulate/mL

Bacteria3,4

< 0.01 CFU/mL

Pyrogens (endotoxins)4

< 0.001 EU/mL

RNases4

< 1 pg/mL

DNases4

< 5 pg/mL

Flow Rate

Up to 2 L/min

1resistivity can also be displayed non-temperature-compensated as required by USP 
2in the appropriate test conditions
3with Millipak® final filter
4with Biopak® polisher
These values are typical and may vary depending on the nature and concentration of contaminants in the feed water.

Milli-Q® Integral pure water (Type 2)

Resistivity at 25 °C1

Typically 10-15 MΩ•cm

TOC

< 30 ppb

Production flow Rate

3 L/h (Milli-Q® Integral 3)
5 L/h (Milli-Q® Integral 5)
10 L/h (Milli-Q® Integral 10)
15 L/h (Milli-Q® Integral 15)

From an E-POD® dispenser with final filter, the following water quality specifications are achieved:

Particulates (size > 0.22 μm)2

< 1 particulate/mL

Bacteria2,3

< 0.1 CFU/mL

Pyrogens (endotoxins)3

< 0.001 EU/mL

RNases3

< 0.01 ng/mL

DNases3

< 4 pg/μL

Flow Rate

Up to 2 L/min

1Resistivity can also be displayed non-temperature-compensated as required by USP 
2with Millipak® final filter
3with Biopak® Polisher

Feed water

Feed water quality

Potable tap water as described in US-EPA, EP and WHO norms

Feed water connection

½” Gaz M

Feed water pressure*

1 - 6 bar

Feed water temperature

5 - 35 °C

* For pressure above 6 bar, a pressure regulator needs to be installed upstream of the system

System Specifications

Production unit

Dimensions (H x W x D)

500 x 332 x 484 mm (19.7 x 13.0 x 19.0 in)

Operating weight

24 - 28 kg (52.9 - 61.7 lb)

Electric power supply voltage

100 - 230 V +/- 10%

Electric power supply frequency

50 - 60 Hz +/- 10%

Milli-Q® Integral main unit data connection

Ethernet (RJ45)

Q-POD® & E-POD® dispensers

Dimensions (H x D)

579 x 230 mm (22.8 x 9.0 in)

Operating weight

4.7 kg (12.1 lb)

Dispenser tubing length

0.8 m (31.5 in)

Distance from production unit to Q-POD®

2.9 m (9.5 ft)

Electric power cable length

2.9 m (9.5 ft)

Q-POD® data connection

Parallel port (25-pin D-Sub)

 

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